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The workforce focused on blocking a protein referred to as synaptotagmin-2, or Syt2. Syt2 is observed over the area on the granules containing mucin. Fusion of such granules Using the cell membrane depends on Syt2 interacting with proteins inside the mobile membrane.
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Ordinarily, mucins are slowly introduced in to the airways, where they take up drinking water and type a skinny layer of protecting mucus that traps pathogens and is easily cleared by cilia.
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In lab tests, SP9 shut down the membrane fusion approach by attaching to Syt2. The scientists up coming analyzed SP9 in human airway cells grown during the lab.
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